Recent Publications

Blackburn DM, Soleimani VD. The hidden cost of somatic mutations on skeletal

muscle regeneration. Nat Aging. 2025 Aug 20. doi: 10.1038/s43587-025-00944-9.

Epub ahead of print. PMID: 40836124.

Sahinyan K, Blackburn DM, Simon MM, Lazure F, Kwan T, Wilson DH, Vahidyeganeh

M, Alsadi N, von Maltzahn J, Yamada Y, Jahani-Asl A, Bourque G, Rudnicki MA,

Soleimani VD. REST/NRSF Preserves muscle stem cell identity by repressing

alternate cell fate. Nat Commun. 2025 Aug 12;16(1):7487. doi:

10.1038/s41467-025-62758-y. PMID: 40796549; PMCID: PMC12343973.

Abu-Nada L, Liu Y, Saleh Al-Hamed F, Ouliass B, Millecamps M, Tran SD,

Ferland G, Soleimani VD, Marino FT, Murshed M. Young bone marrow transplantation

delays bone aging in old mice. Exp Gerontol. 2025 Apr;202:112704. doi:

10.1016/j.exger.2025.112704. Epub 2025 Feb 24. PMID: 39914580.

Burban A, Sharanek A, Hernandez-Corchado A, Najafabadi HS, Soleimani VD,

Jahani-Asl A. Targeting glioblastoma with a brain-penetrant drug that impairs

brain tumor stem cells via NLE1-Notch1 complex. Stem Cell Reports. 2024 Nov

12;19(11):1534-1547. doi: 10.1016/j.stemcr.2024.09.007. Epub 2024 Oct 17. PMID:

39423824; PMCID: PMC11589194.

Blackburn DM, Sahinyan K, Hernández-Corchado A, Lazure F, Richard V, Raco L,

Perron G, Zahedi RP, Borchers CH, Lepper C, Kawabe H, Jahani-Asl A, Najafabadi

HS, Soleimani VD. The E3 ubiquitin ligase Nedd4L preserves skeletal muscle stem

cell quiescence by inhibiting their activation. iScience. 2024 Jun

11;27(7):110241. doi: 10.1016/j.isci.2024.110241. PMID: 39015146; PMCID:

PMC11250905.

Rasool D, Burban A, Sharanek A, Madrigal A, Hu J, Yan K, Qu D, Voss AK, Slack

RS, Thomas T, Bonni A, Picketts DJ, Soleimani VD, Najafabadi HS, Jahani-Asl A.

PHF6-mediated transcriptional control of NSC via Ephrin receptors is impaired in

the intellectual disability syndrome BFLS. EMBO Rep. 2024 Mar;25(3):1256-1281.

doi: 10.1038/s44319-024-00082-0. Epub 2024 Mar 1. PMID: 38429579; PMCID:

PMC10933485.

Lazure F, Blackburn DM, Soleimani VD. Transcriptional Profiling of Skeletal

Muscle Stem Cells After In Vivo Engraftment into a Heterologous Niche

Environment. Curr Protoc. 2023 Aug;3(8):e877. doi: 10.1002/cpz1.877. PMID:

37638781.

Lazure F, Farouni R, Sahinyan K, Blackburn DM, Hernández-Corchado A, Perron

G, Lu T, Osakwe A, Ragoussis J, Crist C, Perkins TJ, Jahani-Asl A, Najafabadi

HS, Soleimani VD. Transcriptional reprogramming of skeletal muscle stem cells by

the niche environment. Nat Commun. 2023 Feb 1;14(1):535. doi:

10.1038/s41467-023-36265-x. PMID: 36726011; PMCID: PMC9892560.

Sahinyan K, Blackburn DM, Soleimani VD. ATAC-Seq of a Single Myofiber from

Mus musculus. Bio Protoc. 2022 Jun 20;12(12):e4452. doi:

10.21769/BioProtoc.4452. PMID: 35990589; PMCID: PMC9362843.

Sharanek A, Raco L, Soleimani VD, Jahani-Asl A. <i>In situ</i> detection of

protein-protein interaction by proximity ligation assay in patient derived brain

tumor stem cells. STAR Protoc. 2022 Jul 19;3(3):101554. doi:

10.1016/j.xpro.2022.101554. PMID: 35880130; PMCID: PMC9307678.

Sharanek A, Raco L, Soleimani VD, Jahani-Asl A. Subcellular fractionation of

brain tumor stem cells. Methods Cell Biol. 2022;170:47-58. doi:

10.1016/bs.mcb.2022.02.006. Epub 2022 Apr 18. PMID: 35811103.

Rasool D, Soleimani VD, Jahani-Asl A. Isolation of Adult Mouse Neural Stem

Cells and Assessment of Self-Renewal by ELDA. Methods Mol Biol.

2022;2515:343-354. doi: 10.1007/978-1-0716-2409-8_21. PMID: 35776362.

Sahinyan K, Blackburn DM, Simon MM, Lazure F, Kwan T, Bourque G, Soleimani

VD. Application of ATAC-Seq for genome-wide analysis of the chromatin state at

single myofiber resolution. Elife. 2022 Feb 21;11:e72792. doi:

10.7554/eLife.72792. PMID: 35188098; PMCID: PMC8901173.

Sahinyan K, Lazure F, Blackburn DM, Soleimani VD. Decline of regenerative

potential of old muscle stem cells: contribution to muscle aging. FEBS J. 2023

Mar;290(5):1267-1289. doi: 10.1111/febs.16352. Epub 2022 Jan 25. PMID: 35029021.

Sharanek A, Burban A, Hernandez-Corchado A, Madrigal A, Fatakdawala I,

Najafabadi HS, Soleimani VD, Jahani-Asl A. Transcriptional control of brain

tumor stem cells by a carbohydrate binding protein. Cell Rep. 2021 Aug

31;36(9):109647. doi: 10.1016/j.celrep.2021.109647. PMID: 34469737.

Blackburn DM, Lazure F, Soleimani VD. SMART approaches for genome-wide

analyses of skeletal muscle stem and niche cells. Crit Rev Biochem Mol Biol.

2021 Jun;56(3):284-300. doi: 10.1080/10409238.2021.1908950. Epub 2021 Apr 7.

PMID: 33823731.

Blackburn DM, Lazure F, Soleimani VD. RNA Sequencing of Single Myofibers

from <i>Mus musculus</i>. Bio Protoc. 2020 Feb 20;10(4):e3525. doi:

10.21769/BioProtoc.3525. PMID: 33654749; PMCID: PMC7842825.

Lazure F, Blackburn DM, Corchado AH, Sahinyan K, Karam N, Sharanek A, Nguyen

D, Lepper C, Najafabadi HS, Perkins TJ, Jahani-Asl A, Soleimani VD. Myf6/MRF4 is

a myogenic niche regulator required for the maintenance of the muscle stem cell

pool. EMBO Rep. 2020 Dec 3;21(12):e49499. doi: 10.15252/embr.201949499. Epub

2020 Oct 13. PMID: 33047485; PMCID: PMC7726801.

Sharanek A, Burban A, Laaper M, Heckel E, Joyal JS, Soleimani VD, Jahani-Asl

A. OSMR controls glioma stem cell respiration and confers resistance of

glioblastoma to ionizing radiation. Nat Commun. 2020 Aug 17;11(1):4116. doi:

10.1038/s41467-020-17885-z. PMID: 32807793; PMCID: PMC7431428.